Toxic epidermal necrosis
☆ ໃນປີ 2022 Stiftung Warentest ຜົນໄດ້ຮັບຈາກເຢຍລະມັນ, ຄວາມພໍໃຈຂອງຜູ້ບໍລິໂພກກັບ ModelDerm ແມ່ນຕໍ່າກວ່າການປຶກສາຫາລືທາງດ້ານການປິ່ນປົວທາງໂທລະສັບເລັກນ້ອຍເທົ່ານັ້ນ.
ລັກສະນະຂອງຜິວແພ້ງ່າຍ Toxic epidermal necrosis
References
Stevens-Johnson Syndrome (SJS) ແລະ Toxic Epidermal Necrolysis (TEN) ແມ່ນເງື່ອນໄຂທີ່ຫາຍາກທີ່ຜິວຫນັງປະສົບກັບ necrosis ຢ່າງກວ້າງຂວາງແລະການຫຼົ່ນລົງ. ໃນດ້ານການປິ່ນປົວ, cyclosporine ມີປະສິດທິພາບສູງສໍາລັບ SJS, ໃນຂະນະທີ່ການປະສົມປະສານຂອງ immunoglobulin intravenous (IVIg) ແລະ corticosteroids ເຮັດວຽກທີ່ດີທີ່ສຸດສໍາລັບກໍລະນີຂອງ SJS ແລະ TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
Toxic epidermal necrolysis (TEN) ເປັນປະຕິກິລິຢາຜິວໜັງຢ່າງຮ້າຍແຮງທີ່ເກີດຈາກຢາບາງຊະນິດ ແລະ ການເຮັດວຽກຂອງລະບົບພູມຄຸ້ມກັນ, ເຮັດໃຫ້ເກີດການຍັບຍັ້ງຂອງຊັ້ນຜິວໜັງຊັ້ນນອກ (epidermis) , ຜົນກະທົບຕໍ່ຜິວໜັງຫຼາຍກວ່າ 30%. TEN ມີອັດຕາການຕາຍຫຼາຍກວ່າ 20%, ເລື້ອຍໆຍ້ອນການຕິດເຊື້ອແລະການຫາຍໃຈຍາກ. ການຢຸດເຊົາຢາທີ່ເຮັດໃຫ້ເກີດປະຕິກິລິຢາ, ສະຫນອງການດູແລສະຫນັບສະຫນູນ, ແລະການນໍາໃຊ້ການປິ່ນປົວເພີ່ມເຕີມສາມາດປັບປຸງຜົນໄດ້ຮັບ. ການສຶກສາທີ່ຜ່ານມາໄດ້ສະແດງໃຫ້ເຫັນວ່າຢາເຊັ່ນ: cyclosporine, tumor necrosis factor alpha inhibitors, ແລະການປະສົມປະສານຂອງ immune globulin intravenous ແລະ corticosteroids ສາມາດເປັນປະໂຫຍດ, ອີງຕາມການທົດລອງຄວບຄຸມແບບສຸ່ມແລະການວິເຄາະຂອງການສຶກສາຫຼາຍ.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
Recent Advances: There is improved understanding of pain and morbidity with regard to the type and frequency of dressing changes. More modern dressings, such as nanocrystalline, are currently favored as they may be kept in situ for longer periods. The most recent evidence on systemic agents, such as corticosteroids and cyclosporine, and novel treatments, are also discussed.
ສາເຫດທົ່ວໄປທີ່ສຸດແມ່ນຢາບາງຊະນິດເຊັ່ນ lamotrigine, carbamazepine, allopurinol, ຢາຕ້ານເຊື້ອ sulfonamide, ແລະ nevirapine. ປັດໃຈສ່ຽງລວມມີ HIV ແລະ lupus erythematosus ທີ່ເປັນລະບົບ. ການປິ່ນປົວໂດຍທົ່ວໄປແມ່ນເກີດຂຶ້ນໃນໂຮງຫມໍເຊັ່ນ: ຢູ່ໃນຫນ່ວຍບໍລິການບາດແຜຫຼືຫ້ອງການດູແລແບບສຸມ.
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ນີ້ແມ່ນພະຍາດທີ່ຮ້າຍແຮງ, ດັ່ງນັ້ນຖ້າສົບຫຼືປາກຂອງທ່ານໄດ້ຮັບຜົນກະທົບຫຼືຜິວຫນັງຂອງທ່ານກາຍເປັນຕຸ່ມໂພງ, ໃຫ້ໄປພົບແພດໄວເທົ່າທີ່ຈະໄວໄດ້.
ຢາທີ່ສົງໃສຄວນຢຸດເຊົາ. (ເຊັ່ນ: ຢາຕ້ານເຊື້ອ, ຢາຕ້ານການອັກເສບທີ່ບໍ່ແມ່ນ steroidal)